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18906399270Dermatan sulfate (DS), once misleadingly named chondroitin sulfate B, is a class of sulfated GAGs composed of repeating disaccharide units (IdoUAa1-3GalNAc) linked by β-1,4 glycosidic bonds. From the perspective of composition and structure, DS is a type of GAGs that is completely different from CS. However, from the perspective of the biosynthetic process, DS is a product resulted from the conversation of GlcUA residues to IdoUA residues in CS chain by the action of C5 epimerase, and thus CS and DS often coexist in a single chain, called CS-DS hybrid chain. A large number of studies have shown that the DS domains in the CS-DS sugar chain usually play a key role in the interaction with proteins and participate in various important physiological and pathological processes together with CS. At present, commercial DS is mainly isolated from animal skin or heparin by-products. However, due to the coexistence of HS, CS, and HA with highly similar physical and chemical properties in tissues, high-purity DS is difficult to prepare.
Products
Product No. | CAS No. | Name | Sizes | Reference Prices (USD) |
DS01 | 54328-33-5 | Chondroitin sulfate B sodium salt;Dermatan sulfate sodium salt 95% | 10mg; 50mg;100mg | $60;$270;$450 |
DS02 | 54328-33-5 | Chondroitin sulfate B sodium salt;Dermatan sulfate sodium salt 95% | 1g;10g;20g | $2,240;$15,000;$27,000 |
DS-Flu | Fluorescein Chondroitin sulfate B sodium salt;Fluorescein Dermatan sulfate sodium salt | 1mg; 5mg;10mg | $160;$600;$1,000 | |
DS-Bio | biotin Chondroitin sulfate B sodium salt;biotin Dermatan sulfate sodium salt | 1mg; 5mg;10mg | $100;$400;$700 |